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Filtered Search Results
Apexbio Technology LLC PF-04929113 (SNX-5422) 908115-27-5 5mg
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PF-04929113 (SNX-5422) [CAS 908115-27-5] is an orally bioavailable water-soluble prodrug of PF-04928473 designed as an inhibitor of heat shock protein 90 (Hsp90) Following oral administration PF-04929113 is rapidly absorbed and converted to its active form PF-04928473 This active metabolite facilitates degradation of HER2 client proteins and demonstrates pronounced antitumor effects in xenograft models including BT-474 and H1650 with minimal observed toxicity at effective doses PF-04928473 additionally suppresses signaling pathways such as p-ERK and p-Akt and reduces angiogenesis markers supporting its use in research on cancer biology and anti-angiogenic strategies
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Medchemexpress LLC 5MPN | 47208-82-2 | MFCD00089445 | 99.9% | 305.33 | C15H19N3O4 | 10MG
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5MPN is a selective, orally active inhibitor of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4), used as a research compound to probe tumor sugar metabolism and inhibit cancer cell proliferation in vitro.
- Selective PFKFB4 inhibition, competitive at the F6P binding site (Ki = 8.6 μM).
- Targets tumor sugar metabolism and suppresses proliferation of multiple human cancer cell lines.
- High purity (~99.9%) suitable for biochemical assays.
- Available in small research quantities such as 10 mg and as 10 mM DMSO solution.
- Molecular weight 305.33 and molecular formula C15H19N3O4 for analytical reference.
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eMolecules 770-12-7 | Phenyl dichlorophosphate | Chem-Impex | MFCD00002067 | 210.980 | C6H5Cl2O2P | 99.000 | ClP(Cl)(=O)Oc1ccccc1 | 25g | 322127601
Phenyl dichlorophosphate | Chem-Impex | 770-12-7 | MFCD00002067 | 210.980 | C6H5Cl2O2P | 99.000 | ClP(Cl)(=O)Oc1ccccc1 | 25g | 322127601
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Medchemexpress LLC HY-13984 5mg Medchemexpress, Mutant EGFR inhibitor CAS:1421373-62-7 Purity:>98%
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Medchemexpress, HY-13984 5mg Mutant EGFR inhibitor CAS:1421373-62-7 Mutant EGFR inhibitor is a potent and selective mutant EGFR inhibitor extracted from patent WO 2013014448 A1; inhibits EGFRL858R, EGFRExon 19 deletion and EGFRT790M. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC JAK-IN-5 hydrochloride | 2751323-21-2 | 99.52% | 511.03 | 100 MG
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JAK-IN-5 hydrochloride is an inhibitor of JAK extracted from patent US20170121327A1, compound example 283.
- Inhibitor of JAK.
- Inhibits STAT6 phosphorylation by 60% in IL-13-induced lung tissue in a mouse model of pSTAT6 induction (oral aspirate, 0.5 mg/mL, 50 μL).
- Inhibits 88% of BALF eosinophils in a male C57 mice model of Alternaria alternata-induced eosinophilic inflammation of the lung (oral aspirate, 0.1-1.0 mg/mL, 50 μL).
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eMolecules Medchem Express | Seladelpar sodium salt | 5mg | 446269888 | HY-19522A | 466.45 | C21H22F3NaO5S
Medchem Express | Seladelpar sodium salt | 5mg | 446269888 | HY-19522A | | 466.450 | C21H22F3NaO5S
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Medchemexpress LLC HY-14656 5g , Diltiazem (hydrochloride) CRD-401 CAS:33286-22-5 Purity:98%
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Medchemexpress, HY-14656 5g Diltiazem (hydrochloride) CRD-401 CAS:33286-22-5 Formula:C22H27ClN2O4S Purity:98% Diltiazem hydrochloride is a Ca 2+ influx inhibitor (slow channel blocker or calcium antagonist). Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-12335 5mg Medchemexpress, UNC0379 CAS:1620401-82-2 Purity:>98%
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Medchemexpress, HY-12335 5mg UNC0379 CAS:1620401-82-2 UNC0379 is a selective, substrate-competitive inhibitor of lysine methyltransferase SETD8 (KMT5A) with an IC50 of 7.3 μM; selective over 15 other methyltransferases. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-15485 5mg Medchemexpress, Zardaverine CAS:101975-10-4 Purity:>98%
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Medchemexpress, HY-15485 5mg Zardaverine CAS:101975-10-4 0 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC E-N-ethyl-N-(6,6-dimethyl-2-hepten-4-ynyl)-3-(2-methyl-2-(3-thienylmethoxy)propyloxy)benzylamine HCl | 204067-52-7 | 98.8% | 476.11 | C27H38ClNO2S | 100 MG
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FR194738 is a research compound that potently inhibits squalene epoxidase and is used to investigate cholesterol biosynthesis in biochemical and cell-based assays. Reported activity includes an IC50 of 9.8 nM in HepG2 cell homogenates and 4.9 nM for inhibition of cholesterol synthesis in intact HepG2 cells. Supplied as a high-purity free base with multiple package sizes and storage recommendations for laboratory use.
- Potent squalene epoxidase inhibition in biochemical and cell assays.
- Demonstrated low-nanomolar IC50 in HepG2 assays.
- Available as a free base with supplier-reported high purity.
- Multiple package sizes for flexible experimental scaling.
- Storage recommendations support compound stability for routine use.
- For research use only; not for human or clinical use.
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Medchemexpress LLC BRD4 Inhibitor-24 | 309951-18-6 | 99.27% | 262.26 | 50 MG
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BRD4 Inhibitor-24 (compound 3U) is a potent BRD4 inhibitor that has demonstrated antitumor activity. It shows IC50 values of 33.7 μM against MCF7 cells and 45.9 μM against K652 cells. This compound has been extracted from patent CN107721975A.
- Potent BRD4 inhibitor.
- Exhibits antitumor activity against MCF7 (IC50: 33.7 μM) and K652 (IC50: 45.9 μM) cells.
- Derived from patent CN107721975A.
- For research use only.
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![eMolecules 1864062-88-3 | Lithium 3-phenyl-1,2,4-oxadiazole-5-carboxylate | ChemScene | MFCD29034260 | 196.090 | C9H5LiN2O3 | 95.000 | [Li+].[O-]C(=O)c1nc(no1)-c1ccccc1 | 100mg | 714102845](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502462968.JPG-250.jpg)
eMolecules 1864062-88-3 | Lithium 3-phenyl-1,2,4-oxadiazole-5-carboxylate | ChemScene | MFCD29034260 | 196.090 | C9H5LiN2O3 | 95.000 | [Li+].[O-]C(=O)c1nc(no1)-c1ccccc1 | 100mg | 714102845
Lithium 3-phenyl-1,2,4-oxadiazole-5-carboxylate | ChemScene | 1864062-88-3 | MFCD29034260 | 196.090 | C9H5LiN2O3 | 95.000 | [Li+].[O-]C(=O)c1nc(no1)-c1ccccc1 | 100mg | 714102845
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Medchemexpress LLC (±)-Darifenacin ((±)-UK-88525) | 133033-93-9 | 99.4% | 426.55 | 100 MG
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(±)-Darifenacin is the racemate of Darifenacin, which is a selective M3 muscarinic receptor antagonist.
- Soluble in DMSO at 100 mg/mL (234.44 mM).
- Store powder at -20°C for 3 years or 4°C for 2 years.
- Store in solvent at -80°C for 2 years or -20°C for 1 year.
- Appears as a solid, white to off-white.
- Related to neurological, eye or ear disease, cancer, neurodegenerative disease, Parkinson's disease, cancer metabolism and metastasis.
- Involved in GPCR/G protein, neuronal signaling, mAChR pathways.
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Medchemexpress LLC 1,3-Dimethoxybenzene | 151-10-0 | 99.99% | 138.17 | 500 G
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1,3-Dimethoxybenzene is a volatile compound characterized by a sweet medicinal odor with notes of hazelnut, resin, and wood. It has been identified as a new volatile component in grape musts from the Douro region and in port wines. This compound can be isolated from port wine extracts through flash chromatography, primarily eluting in the 60% hexane/40% diethyl ether fraction. The product is intended for research use only.
- Volatile compound with a sweet medicinal odor carrying hazelnut, resinous, and woody notes.
- Identified as a new volatile component of Douro region grape musts and port wines.
- High purity of 99.99%.
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Medchemexpress LLC 2-(4-Chloro-phenoxy)-phenylacetic acid | 25563-04-6 | 99.6% | 262.69 | 100 MG
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2-(4-Chloro-phenoxy)-phenylacetic acid is a drug intermediate used for the synthesis of various active compounds. This product is intended for research use only, and MedChemExpress does not sell to patients.
- Suitable for high-speed applications
- Room temperature shipping in continental US
- Storage in powder form: -20°C for 3 years, 4°C for 2 years
- Storage in solvent: -80°C for 6 months, -20°C for 1 month
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